Title of article
Regulation of p53R2 and its role as potential target for cancer therapy
Author/Authors
Wang، نويسنده , , Xin and Zhenchuk، نويسنده , , Anna and Wiman، نويسنده , , Klas G. and Albertioni، نويسنده , , Freidoun، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2009
Pages
7
From page
1
To page
7
Abstract
p53R2, a recently discovered small subunit of human ribonucleotide reductase, is believed to play essential roles in DNA repair, mtDNA synthesis, and protection against oxidative stress. Because of the positive correlation between the level of this protein and drug sensitivity and tumor invasiveness, it constitutes a potential target for anticancer drugs as well as a diagnostic marker in cancer.
Keywords
p53R2 , p53 , Nucleoside analogues , leukemia , chemotherapy
Journal title
Cancer Letters
Serial Year
2009
Journal title
Cancer Letters
Record number
1813503
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