Clinical Presentation and Final Outcome in Definite Cases of Influenza A (H1N1) in Kashan, Iran

Background: Influenza A (H1N1) imposed a considerable burden on our health community. This study was conducted to evaluate the clinical and paraclinical pattern of the disease in influenza A (H1N1) patients in Kashan. Materials and Methods: This descriptive study was carried out on 87 definite cases of pandemic influenza A (H1N1) diagnosed from July to January 2009 in Kashan. The clinical and paraclinical information were collected and analyzed by SPSS-13. Results: The majority of patients were in age group 16-25 years and 50.6% of patients were male. The most common clinical symptoms were fever (92%), cough (78.2%) and dyspnea (54%). The most important paraclinical findings were: leokocytosis (41.3%) increased ESR (46.6%), positive CRP (48.7%). The mortality was seen in 8 patients (9.2%). Conclusion: Regarding to majority of death has occurred in patients with underlying disease, annual prophylaxis by influenza vaccine and early treatment to prevent of morbidity and mortality is recommended.