Title of article
Tandem triplication and quadruplication of chromosome 21 in childhood acute lymphoblastic leukemia
Author/Authors
Marta S. and Baialardo، نويسنده , , Edgardo M. and Felice، نويسنده , , Marيa S. and Rossi، نويسنده , , Jorge and Barreiro، نويسنده , , Cristina and Gallego، نويسنده , , Marta S.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
3
From page
43
To page
45
Abstract
A 5-year-old girl with ALL was shown to have a leukemic clone characterized by a triplication and quadruplication of chromosome 21, arranged in tandem, at diagnosis and relapse, respectively. To our knowledge, this is the second report of this chromosomal anomaly in ALL, which was confirmed by in situ staining. The karyotype evolution in the leukemic clone from triplication to quadruplication at relapse emphasis the association of chromosome 21 with hematopoietic malignancies.
Journal title
Cancer Genetics and Cytogenetics
Serial Year
1996
Journal title
Cancer Genetics and Cytogenetics
Record number
1819797
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