Title of article
Ring Chromosomes in a Malignant Mesenchymoma
Author/Authors
van Kessel، نويسنده , , A.Geurts and Simons، نويسنده , , A and Grandjean Perrenod Comtesse، نويسنده , , P.P.F and Siepman، نويسنده , , A and Janssen، نويسنده , , I and Suijkerbuijk، نويسنده , , R.F. and Forus، نويسنده , , Maciej Pruszczynski، نويسنده , , M and Veth، نويسنده , , R.P.H، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
4
From page
119
To page
122
Abstract
We report, for the first time, the cytogenetic and molecular genetic constitution of a human mesenchymoma. As in several other soft tissue sarcomas, supernumerary ring and rod-shaped marker chromosomes were observed next to an otherwise normal diploid karyotype. Comparative genomic in situ hybridization and whole chromosome painting experiments revealed that chromosome 1q21–q25 and 12q14–q15 sequences were amplified, and that these sequences resided on the supernumerary marker chromosomes. We assume that, in this malignant mesenchymoma, the observed chromosomal anomalies may be associated with its well differentiated liposarcomatous component.
Journal title
Cancer Genetics and Cytogenetics
Serial Year
1999
Journal title
Cancer Genetics and Cytogenetics
Record number
1821807
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