Title of article
A Novel t(11;12)(q23–24;q24) in a Case of Minimally-Differentiated Acute Myeloid Leukemia (AML-M0)
Author/Authors
Cox، نويسنده , , M.Christina and Scanzani، نويسنده , , Alessandra and Del Poeta، نويسنده , , Giovanni and Venditti، نويسنده , , Adriano and Panetta، نويسنده , , Paola and Derme، نويسنده , , Valentina and Sgro، نويسنده , , Rosanna and Masi، نويسنده , , Mario and Amadori، نويسنده , , Sergio، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
4
From page
76
To page
79
Abstract
Acute myeloid leukemia with minimal signs of myeloid differentiation (AML-M0) is a recent addition to the FAB group classification. Chromosome data is scarce, but existing reports describe a high incidence of complex karyotypes and myelodysplastic syndrome-like chromosome alterations, while single chromosome translocations have rarely been reported. We describe the case of a 60-year-old woman diagnosed with AML-M0 with a novel translocation t(11;12)(q23–24;q24) as the sole karyotypic marker. Fluorescence in situ hybridization analysis to assess MLL gene splitting did not show rearrangement of this oncogene.
Journal title
Cancer Genetics and Cytogenetics
Serial Year
2000
Journal title
Cancer Genetics and Cytogenetics
Record number
1822688
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