Title of article
Two novel 3,4-seco-trinorlanostane triterpenoids isolated from Ganoderma fornicatum
Author/Authors
Niu، نويسنده , , Xuemei and Qiu، نويسنده , , Minghua and Li، نويسنده , , Zhongrong and Lu، نويسنده , , Yang and Cao، نويسنده , , Peng and Zheng، نويسنده , , Qitai، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
5
From page
2989
To page
2993
Abstract
Two novel 3,4-seco-25,26,27-trinorlanostane triterpeniod compounds, fornicatins A and B (1 and 2) have been isolated from the fruiting body of G. fornicatum. The structural elucidation of 1 and 2 were accomplished by extensive NMR analysis. The relative stereochemistry of 2 was established by single crystal X-ray crystallography, which also confirmed the novel carbon skeleton of the new triterpenoid. An ether linkage of C-4 with C-7 in 1 is unprecedented in natural triterpenoids. Both compounds were tested for their inhibitory effects on rabbit platelet aggregation induced by PAF, ADP, or AA.
Keywords
Ganodermataceae , Trinorlanostane , Fornicatins A and B , NMR , X-Ray , Ganoderma fornicatum
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1841229
Link To Document