• Title of article

    Bergman cycloaromatization of imidazole-fused enediynes: the remarkable effect of N-aryl substitution

  • Author/Authors

    Zhao، نويسنده , , Zhengrong and Peng، نويسنده , , Yunshan and Dalley، نويسنده , , N.Kent and Cannon، نويسنده , , John R. and Peterson، نويسنده , , Matt A، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2004
  • Pages
    4
  • From page
    3621
  • To page
    3624
  • Abstract
    A series of N-aryl substituted `imidazole-fusedʹ (Z) 3-ene-1,5-diynes was prepared and kinetic parameters for their Bergman cycloaromatization reactivities were determined. N-Arylation enhanced rates relative to N-alkyl derivatives by up to sevenfold (ANOVA p<0.0001). The greatest enhancement was exhibited by the N-phenyl derivative (sevenfold at 145 °C).
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2004
  • Journal title
    Tetrahedron Letters
  • Record number

    1841466