Title of article
Asymmetric synthesis of a new simplified dynemicin analogue equipped with a handle
Author/Authors
Banfi، نويسنده , , Luca and Basso، نويسنده , , Andrea and Gandolfo، نويسنده , , Valentina and Guanti، نويسنده , , Giuseppe and Riva، نويسنده , , Renata، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
3
From page
4221
To page
4223
Abstract
The new simplified dynemicin analogue 16 was prepared enantio- and diastereoselectively in 17 steps starting from monoacetate (S) 7. It is equipped with a side arm containing a protected primary alcoholic function (`handleʹ), which can be used for conjugation with DNA-complexing agents or for devising new types of trigger.
Keywords
Enediynes , Quinoline , Corey–Fuchs reaction , Dynemicin
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1841734
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