Title of article
Aza analogs of kainoids by dipolar cycloaddition
Author/Authors
Di، نويسنده , , Mingping and Rein، نويسنده , , Kathleen S.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
3
From page
4703
To page
4705
Abstract
The 1,3-dipolar cycloadditions of diazoalkanes with trans-diethyl glutaconate yield 1-pyrazolines, which isomerize to 2-pyrazolines or are oxidized to pyrazoles. The 2-pyrazolines may serve as precursors to novel glutamate analogs or aza analogs of kainoids. The regioselectivity of the 1,3-dipolar cycloadditions of diazoalkanes and trans-diethyl glutaconate and isomerization of the 1-pyrazolines to 2-pyrazolines are evaluated.
Keywords
dipolar cycloaddition , Kainoids , Pyrazole , Pyrazolines
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1842067
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