Title of article
Mild electrophilic halogenation of chloropyridines using CCl4 or C2Cl6 under basic phase transfer conditions
Author/Authors
Joshi، نويسنده , , Ashutosh V. and Baidossi، نويسنده , , Mubeen and Qafisheh، نويسنده , , Nida and Chachashvili، نويسنده , , Elsa and Sasson، نويسنده , , Yoel، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
3
From page
5061
To page
5063
Abstract
Effective chlorination of 2,3,5,6-tetrachloropyridine to pentachloropyridine was realized under mild phase transfer conditions with carbon tetrachloride and 50% NaOH or solid K3PO4. Mechanistic study of this reaction indicated the possibility of an aromatic carbanionic intermediate. Hexachloroethane was established as a more selective electrophilic chlorination agent.
Keywords
Polyhalomethane , potassium phosphate , Aromatic carbanion , phase transfer , Halogenation
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1842225
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