Title of article
Nitrobenzylation of α-carbonyl ester derivatives using TDAE approach
Author/Authors
Giuglio-Tonolo، نويسنده , , Gamal and Terme، نويسنده , , Thierry and Médebielle، نويسنده , , Maurice and Vanelle، نويسنده , , Patrice، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
4
From page
5121
To page
5124
Abstract
A series of 2-hydroxy-propionic acid ethyl ester derivatives was prepared in good yields by reaction of o- and p-nitrobenzyl chlorides (1, 8) with various α-carbonyl esters in presence of tetrakis(dimethylamino)ethylene (TDAE). This reaction was generalized to α-ketolactam and α-ketomalonate.
Keywords
p-nitrobenzyl chloride , ?-Carbonyl ester , ?-Hydroxy ester , TDAE
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1842248
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