Title of article
New access to fluorinated ketoglycolic acid derivatives from trifluoropyruvamides
Author/Authors
Colin، نويسنده , , Thomas and El Ka??m، نويسنده , , Laurent and Gaultier، نويسنده , , Laetitia and Grimaud، نويسنده , , Laurence and Gatay، نويسنده , , Laurent and Michaut، نويسنده , , Valérie، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
3
From page
5611
To page
5613
Abstract
Hydrates of trifluoropyruvamides are readily obtained from isocyanides and trifluoroacetic anhydride. Under catalysis with secondary amines, these hydrates were successfully reacted with various methylketones to form fluorinated aldol type compounds. The effect of the amine is discussed as well as Henry type additions with nitromethane.
Keywords
Pyruvamide , Trifluoromethyl group , isocyanide , enamines
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1842523
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