Title of article
Characterization and Quantitation of Extracellular Collagen Matrix in Myocardium of Pigs with Spontaneously Occurring Hypertrophic Cardiomyopathy
Author/Authors
Chiu، نويسنده , , Yung-Tsung and Liu، نويسنده , , Si-kwang and Liu، نويسنده , , Michael and Chen، نويسنده , , S.P. and LIN، نويسنده , , Y.H and Mao، نويسنده , , Simon J.T and Chu، نويسنده , , Redmen، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
7
From page
169
To page
175
Abstract
The extracellular matrix between cardiocytes has been suggested to play an important role in maintaining the structure and function of the heart. The purpose of this study was to elucidate the morphological changes in the collagen of the extracellular matrix (ECM) in the hearts of pigs with hypertrophic cardiomyopathy. Sixty pigs diagnosed with hypertrophic cardiomyopathy from 605 purebred Landrace pigs ages 6 to 9 months were used in this study. Morphologically, these pigs with hypertrophic cardiomyopathy had increased heart weight and heart-to–body weight ratio, thickening of the left ventricular (LV) and right ventricular (RV) free walls and septum, disorientation of cardiocytes, myocardial fibrosis, and intramural coronary arteriosclerosis. Similar observations have been described in our preliminary report
Journal title
Cardiovascular Pathology
Serial Year
1999
Journal title
Cardiovascular Pathology
Record number
1842788
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