Title of article
Alternatives to 1-H-tetrazole in the preparation of phosphonate diesters and phosphonamidates from phosphonyl dichlorides
Author/Authors
Maung، نويسنده , , Jack and Mallari، نويسنده , , Jeremy P. and Choy، نويسنده , , Cindy J. and Berkman، نويسنده , , Clifford E.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
3
From page
6497
To page
6499
Abstract
5-Ethylthio-1-H-tetrazole (SET) and 4,5-dicyanoimidazole (DCI) were examined as alternatives to 1-H-tetrazole to mediate the synthesis of phosphonate diesters and phosphonamidates from phosphonyl dichlorides through a two-step one-pot reaction in various organic solvents. SET and DCI were comparable to 1-H-tetrazole for catalyzing these reactions. SET afforded slightly greater yields than DCI while benzene was universally the best solvent for this reaction.
Keywords
Phosphonamidate , 5-Ethylthio-1-H-tetrazole , 4 , 5-Dicyanoimidazole , 1-H-Tetrazole , Phosphonate diester
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1843045
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