Title of article
Homotropic negative allostery in alkali metal ion recognition by biscalix[4]arene-based receptor
Author/Authors
Nabeshima، نويسنده , , Tatsuya and Saiki، نويسنده , , Toshiyuki and Sumitomo، نويسنده , , Keiko and Akine، نويسنده , , Shigehisa، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
3
From page
6761
To page
6763
Abstract
A novel host which shows homotropic and negative allostery for alkali metal ion recognition is constructed by utilizing a biscalix[4]arene skeleton bearing biphenyls and ester moieties. As the ionic radius of the guest increases, recognition of the second guest is suppressed more effectively. A larger ion changes the structure of the first binding site more drastically to cause conformational change unfavorable for the guest binding of the second site.
Keywords
Calixarene , Host–guest , Multi-point receptor , cooperativity , alkali metal
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1843148
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