Title of article
Facile one-step synthesis of N-α-Boc-1-alkyl-l-histidines
Author/Authors
Kaur، نويسنده , , Navneet and Monga، نويسنده , , Vikramdeep and Jain، نويسنده , , Rahul، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
3
From page
6883
To page
6885
Abstract
N-α-Boc-l-Histidine upon direct τ(N-1) ring alkylation with various alkyl halides in the presence of sodium hydride in DMF or CH3CN easily afforded N-α-Boc-1-alkyl-l-histidines 2a–f. The reaction works equally well in either DMF or CH3CN as solvent, however, CH3CN is preferred due to ease of reaction work-up.
Keywords
Nonproteinogenic amino acids , N-?-Boc-1-Alkyl-l-histidines , histidine
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1843196
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