Title of article
Synthesis of 1,2,3,4-tetrahydroisoquinolines and 2,3,4,5-tetrahydro-1H-2-benzazepines combining sequential palladium-catalysed ortho alkylation/vinylation with aza-Michael addition reactions
Author/Authors
Ferraccioli، نويسنده , , Raffaella and Carenzi، نويسنده , , Davide and Catellani، نويسنده , , Marta، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
5
From page
6903
To page
6907
Abstract
1-Substituted 1,2,3,4-tetrahydroisoquinolines and 2,3,4,5-tetrahydro-1H-2-benzazepines were synthesised from o-iodoalkylbenzene, N-Cbz-bromoalkylamine and an electron-poor olefin through a one-pot palladium-catalysed sequence involving ortho alkylation, alkenylation and intramolecular aza-Michael reaction.
Keywords
4-Tetrahydroisoquinolines , 5-Tetrahydro-1H-2-benzazepine , PALLADIUM , 2 , 3 , Catalysis , 4 , 3 , 1 , 2 , Aza-Michael
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1843206
Link To Document