Title of article
Synthesis of (+)-(1S,2R) and (−)-(1R,2S)-2-aminocyclobutane-1-carboxylic acids
Author/Authors
Gauzy، نويسنده , , Christine and Pereira، نويسنده , , Elisabeth and Faure، نويسنده , , Sophie and Aitken، نويسنده , , David J.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
3
From page
7095
To page
7097
Abstract
(+)-(1S,2R) and (−)-(1R,2S)-2-aminocyclobutane-1-carboxylic acids have been prepared in >97% ee and in 33% and 20% overall yields starting from a single, chiral, bicyclic compound perceived as a chiral uracil equivalent. Construction of the cyclobutane ring is achieved via a [2+2] photocycloaddition reaction of this chiral precursor with ethylene.
Keywords
?-Amino acid , cyclobutane , stereoselective synthesis
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1843289
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