Title of article
General facile synthesis of 2,5-diarylheteropentalenes
Author/Authors
Petr Vachal، نويسنده , , Petr and Toth، نويسنده , , Leslie M.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
5
From page
7157
To page
7161
Abstract
Palladium-catalyzed cross-coupling reactions of various heteropentalene derivatives were systematically studied. A general three-step synthesis of 2,5-diarylheteropentalenes involving two Suzuki or Negishi couplings and a regiospecific bromination was developed. Nonsymmetrical 2,5-diaryl-furans, thiophenes, pyrroles, 1,3-thiazoles, 1,3-oxazoles, 1,3,4-thiadiazoles, and 1,3,4-oxadiazoles were prepared in 31–67% isolated yield (three steps).
Keywords
5-Diarylheteropentalenes , Suzuki , Bromination , Catalysis , Heterocycles , 2
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1843311
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