Title of article
Catalytic, asymmetric synthesis of α-acetoxy amides
Author/Authors
North، نويسنده , , Michael and Parkins، نويسنده , , Adrian W. and Shariff، نويسنده , , Atiya N.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
3
From page
7625
To page
7627
Abstract
Non-racemic cyanohydrin acetates are readily available from aldehydes and potassium cyanide/acetic anhydride by use of bimetallic titanium (salen) catalyst 1. Treatment of the cyanohydrin acetates with a platinum(II) phosphinito catalyst 3 under neutral conditions results in chemoselective hydrolysis to the corresponding α-acetoxy amides in a racemization free process.
Keywords
Titanium , Cyanohydrin , amide , Asymmetric catalysis , Platinum
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1843477
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