Title of article
Synthetic studies towards anti-SARS agents: application of an indium-mediated allylation of α-aminoaldehydes as the key step towards an intermediate
Author/Authors
Chng، نويسنده , , Shu-Sin and Hoang، نويسنده , , Truong-Giang and Wayne Lee، نويسنده , , Wei-Woon and Tham، نويسنده , , Mun-Pun and Ling، نويسنده , , Hui Yvonne and Loh، نويسنده , , Teck-Peng، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
4
From page
9501
To page
9504
Abstract
AG7088 was identified as a good starting point for modification, leading to an efficient and bio-available inhibitor for the SARS coronavirus main proteinase (SARS-CoV Mpro). Synthesis of intermediate 1 and analogues proceeded via a highly diastereoselective indium-mediated allylation of α-aminoaldehydes.
Keywords
AG7088 , Indium-mediated allylation , diastereoselective , Anti-SARS agents
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1844240
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