Title of article
Total synthesis of pawhuskin C: a directed ortho metalation approach
Author/Authors
Neighbors، نويسنده , , Jeffrey D. and Salnikova، نويسنده , , Maya S. and Wiemer، نويسنده , , David F.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
4
From page
1321
To page
1324
Abstract
The total synthesis of the opioid modulator pawhuskin C has been accomplished in eight steps from methyl 3,5-dihydroxybenzoate. The key step in this sequence is a directed ortho metalation reaction conducted without protection of a benzylic alcohol and thus presumed to involve a formal dianion intermediate.
Keywords
Pawhuskin , Directed ortho metallation
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1844851
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