Title of article
Asymmetric hydrogenation of imines catalyzed by iridium complexes with phosphine–phosphite ligands: importance of backbone flexibility
Author/Authors
Vargas، نويسنده , , Sergio and Rubio، نويسنده , , Miguel and Suلrez، نويسنده , , Andrés and Pizzano، نويسنده , , Antonio، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
4
From page
2049
To page
2052
Abstract
Chiral phosphine–phosphites provide an alternative class of ligands for the iridium catalyzed enantioselective hydrogenation of imines. Optimization of ligand structure has afforded enantioselectivities up to 84% ee in the reduction of N-aryl imines. A significant influence of backbone nature on enantioselectivity has also been observed.
Keywords
asymmetric hydrogenation , chiral amines , Phosphine–phosphites
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1845144
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