Title of article
A cysteine-appended deoxyuridine for the postsynthetic DNA modification using native chemical ligation
Author/Authors
Takeda، نويسنده , , Shuji and Tsukiji، نويسنده , , Shinya and Nagamune، نويسنده , , Teruyuki، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
4
From page
2235
To page
2238
Abstract
A new deoxyuridine derivative 6 bearing a cysteine group at the C5 position was synthesized and incorporated into oligodeoxynucleotide (ODN) by phosphoramidite chemistry. The postsynthetic DNA modification of the cysteine-containing ODN using native chemical ligation with thioesters of biotin and green fluorescent protein variant was successfully demonstrated.
Keywords
native chemical ligation , Deoxyuridine , Intein , DNA
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1845213
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