Title of article
Mild copper-catalyzed N-arylation of azaheterocycles with aryl halides
Author/Authors
Kuil، نويسنده , , Mark and Bekedam، نويسنده , , E. Koen and Visser، نويسنده , , Gerben M. and van den Hoogenband، نويسنده , , Adri and Terpstra، نويسنده , , Jan Willem and Kamer، نويسنده , , Paul C.J. and van Leeuwen، نويسنده , , Piet W.N.M. and van Strijdonck، نويسنده , , Gino P.F van Strijdonck، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
5
From page
2405
To page
2409
Abstract
A highly efficient copper(I)-catalyzed N-arylation of azaheterocycles with various aryl halides is reported. The N-arylation reaction can be carried out using as low as 0.5 mol % of (Cu(I)OTf)2·PhH and 1.0 mol % of 4,7-dichloro-1,10-phenanthroline as the ligand. Furthermore, cheap and stable copper precursors like Cu(I)I and Cu(II)(OAc)2·H2O and the cheap and mild base K2CO3 can be used.
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1845278
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