Title of article
Superacid-promoted reactions of pyrazolecarboxaldehydes and the role of dicationic electrophiles
Author/Authors
Klumpp، نويسنده , , Douglas A. and Kindelin، نويسنده , , Patrick J. and Li، نويسنده , , Ang، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
5
From page
2931
To page
2935
Abstract
Pyrazolecarboxaldehydes react in the Brønsted superacid triflic acid (CF3SO3H, TfOH) to generate electrophilic intermediates capable of reacting with benzene in condensation reactions. Appropriately substituted pyrazoles may also undergo intramolecular Friedel–Crafts-type reactions. It is proposed that the pyrazolecarboxaldehydes and related systems form diprotonated intermediates in these reactions.
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1845459
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