Title of article
A simple and efficient method for α-bromination of carbonyl compounds using N-bromosuccinimide in the presence of silica-supported sodium hydrogen sulfate as a heterogeneous catalyst
Author/Authors
Das، نويسنده , , Biswanath and Venkateswarlu، نويسنده , , Katta and Mahender، نويسنده , , Gurram and Mahender، نويسنده , , Ibram، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
4
From page
3041
To page
3044
Abstract
α-Bromination of carbonyl compounds (cyclic and acyclic ketones, amides and β-ketoesters) has been achieved efficiently by treatment with N-bromosuccinimide (NBS) and catalyzed by silica-supported sodium hydrogen sulfate (NaHSO4·SiO2). The products were formed in high yields under mild reaction conditions and in short reaction times.
Keywords
carbonyl compounds , ?-Bromination , NaHSO4·SiO2 , Heterogeneous catalyst , NBS
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1845494
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