Title of article
First organophosphorus radical-mediated cyclisations to afford medium-sized rings: eight-membered lactones and seven- and eight-membered lactams
Author/Authors
Lang، نويسنده , , Stuart and Corr، نويسنده , , Michael and Muir، نويسنده , , Neil and Khan، نويسنده , , Tanweer A. and Schِnebeck، نويسنده , , Franziska and Murphy، نويسنده , , John A. and Payne، نويسنده , , Andrew H. and Williams، نويسنده , , Andrew C.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
4
From page
4027
To page
4030
Abstract
The phosphorus based radical precursors N-ethylpiperidine hypophosphite (EPHP) and diethylphosphine oxide (DEPO) are efficient reagents for carrying out the formation of seven- and eight-membered rings. Esters and amides were successfully converted into the corresponding eight-membered lactones and seven- and eight-membered lactams in good to excellent yields.
Keywords
DEPO , EPHP , Phosphorus , Cyclisation , radical
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1845872
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