Title of article
Enantioselective and diastereoselective synthesis of fluorinated dipeptides by late electrophilic fluorination
Author/Authors
Mohar، نويسنده , , Barbara and Sterk، نويسنده , , Damjan and Ferron، نويسنده , , Laurent and Cahard، نويسنده , , Dominique، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
3
From page
5029
To page
5031
Abstract
A series of optically enriched monofluorinated dipeptides incorporating an α-fluoro-α-amino acid were prepared by enantio- and diastereoselective electrophilic fluorination. This previously unsuccessful approach to fluorinated dipeptides can now be achieved with up to 73:27 enantiomeric ratio and high >98:2 diastereomeric ratio.
Keywords
Electrophilic fluorination , Dipeptide , enantioselective synthesis , Fluorine chemistry , Amino acid
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1846217
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