Title of article
Asymmetric synthesis of 3,3-disubstituted isoindolinones
Author/Authors
Comins، نويسنده , , Daniel L. and Hiebel، نويسنده , , Anne-Cécile، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
4
From page
5639
To page
5642
Abstract
An anionic chiral auxiliary-mediated asymmetric alkylation of carbamate 2 affords 3,3-disubstituted isoindolinones 3 in moderate to high de. The chiral auxiliary can be removed and recovered under mild conditions, and the resulting enantiopure lactams further elaborated.
Keywords
chiral auxiliary , asymmetric synthesis , isoindolinones
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1846438
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