Title of article
Hydrogen-bond directed palladium-catalyzed allylic substitution of cyclic substrates
Author/Authors
Cook، نويسنده , , Gregory R. and Saraswathiamma، نويسنده , , Manjusha، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
4
From page
6491
To page
6494
Abstract
The regioselectivity of the Pd-catalyzed allylic substitution of cyclic substrates possessing an adjacent amide functional group was investigated. With imide-like nucleophiles, six-membered ring substrates were found to proceed with a high level of regiodirection whereas hydrogen-bond directed addition was not a significant factor in the five-membered ring substrates.
Keywords
allylic substitution , regioselectivity , hydrogen-bonding , Palladium catalysis
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1846659
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