Title of article
NO as temporary guanidino-protecting group provides efficient access to Pbf-protected argininic acid
Author/Authors
Cupido، نويسنده , , Tommaso and Spengler، نويسنده , , Jan and Burger، نويسنده , , Klaus and Albericio، نويسنده , , Fernando، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
3
From page
6733
To page
6735
Abstract
Pbf-protected argininic acid [H–OArg(Pbf)–OH], a building block for Fmoc-solid phase peptide synthesis, is obtained in high yield when a large excess of nitrosating agent is used in conjunction with intermediate Nδ-nitrosyl protection and Nδ-denitrosation in aqueous acidic medium.
Keywords
Depsipeptides , arginine , Side-reactions , Solid phase peptide synthesis
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1846752
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