Title of article
Edulisones A and B, two epimeric benzo[b]oxepine derivatives from the bark of Aglaia edulis
Author/Authors
Kim، نويسنده , , Soyoung and Su، نويسنده , , Bao-Ning and Riswan، نويسنده , , Soedarsono and Kardono، نويسنده , , Leonardus B.S. and Afriastini، نويسنده , , Johar J. and Gallucci، نويسنده , , Judith C. and Chai، نويسنده , , Heebyung and Farnsworth، نويسنده , , Norman R. and Cordell، نويسنده , , Geoffrey A. and Swanson، نويسنده , , Steven M. and Kinghorn، نويسنده , , A. Douglas، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
4
From page
9021
To page
9024
Abstract
Two benzo[b]oxepine derivatives, edulisones A (1) and B (2), were isolated from the bark of Aglaia edulis, collected in Indonesia. The relative stereochemistry of 1 was determined by single-crystal X-ray diffraction analysis. Treatment of compounds 1 and 2 with lithium hydroxide produced the same hydrolysis products, 1a and 1b, as a result of cleavage of the pyrrolidine ring to an alkylated amide mixture in each case, which demonstrated that these substances are epimeric at their 2-aminopyrrolidine moiety.
Keywords
Epimers , Edulisones A and B , X-ray analysis , alkaline hydrolysis , Aglaia edulis , Meliaceae , NMR data
Journal title
Tetrahedron Letters
Serial Year
2005
Journal title
Tetrahedron Letters
Record number
1847930
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