• Title of article

    Studies on the Biginelli reaction: a mild and selective route to 3,4-dihydropyrimidin-2(1H)-ones via enamine intermediates

  • Author/Authors

    Mabry، نويسنده , , John and Ganem، نويسنده , , Bruce، نويسنده ,

  • Issue Information
    دوماهنامه با شماره پیاپی سال 2006
  • Pages
    2
  • From page
    55
  • To page
    56
  • Abstract
    l-Proline methyl ester hydrochloride was found to be an effective catalyst for assembling (±)-dihydropyrimidinones under mild conditions. Mechanistic insights into the useful selectivity elements of this amine-catalyzed process are also reported.
  • Keywords
    Biginelli , Dihydropyrimidinones , enamines
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2006
  • Journal title
    Tetrahedron Letters
  • Record number

    1847965