Title of article
A novel one-pot synthesis of hydroximoyl chlorides and 2-isoxazolines using N-tert-butyl-N-chlorocyanamide
Author/Authors
Kumar، نويسنده , , Vinod and Kaushik، نويسنده , , M.P.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
4
From page
1457
To page
1460
Abstract
Treatment of aldoximes with N-tert-butyl-N-chlorocyanamide gave hydroximoyl chlorides in quantitative yields in less than a minute, which on dehydrohalogenation in the presence of triethylamine gave the corresponding nitrile oxides. The nitrile oxides underwent 1,3-dipolar addition to dipolarophiles and gave 2-isoxazolines in excellent yields under mild conditions.
Keywords
N-tert-Butyl-N-chlorocyanamide , Hydroximoyl chlorides , Dipolarophiles , N-phenylmaleimide , aldoximes , 2-Isoxazolines
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1849021
Link To Document