Title of article
Reductive opening of glycal derived highly functionalized 2,3-epoxy-1-iodides with zinc dust: an efficient method for the synthesis of acyclic long chain polyhydroxylated terminal alkenic alcohols
Author/Authors
Reddy، نويسنده , , L. Vijaya Raghava and Sagar، نويسنده , , Ram and Shaw، نويسنده , , Arun K.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
4
From page
1753
To page
1756
Abstract
The synthesis of densely functionalized acyclic long chain terminal alkenic alcohols was achieved by reductive opening of glycal derived 2,3-epoxy-1-iodides, with commercial zinc dust alone in a short reaction time with excellent yields involving a simple reaction procedure and easy work-up. A mechanism involving an organometallic intermediate is proposed.
Keywords
2 , zinc dust , 3-Epoxy-1-iodide , Terminal alkenic alcohol , Sharpless epoxidation , selective reduction
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1849182
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