Title of article
Asymmetric addition reactions of Grignard reagents to chiral 2-trifluoromethyl tert-butyl (Ellman) sulfinimine–ethanol adducts
Author/Authors
Kuduk، نويسنده , , Scott D. and Marco، نويسنده , , Christina Ng Di and Pitzenberger، نويسنده , , Steven M. and Tsou، نويسنده , , Nancy، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
5
From page
2377
To page
2381
Abstract
The addition of Grignard reagents to chiral trifluoromethyl tert-butyl sulfinimine–ethanol adducts affords protected trifluoromethylamines in high yields with good to excellent diastereoselectivities. The stereochemical outcome of the addition is opposite to that expected via a chelation controlled transition state.
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1849434
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