Title of article
Expedient synthesis of 1-vinylpyrrole-2-carbaldehydes
Author/Authors
Mikhaleva، نويسنده , , Al’bina I. and Zaitsev، نويسنده , , Alexey B. and Ivanov، نويسنده , , Andrey V. and Schmidt، نويسنده , , Elena Yu. and Vasilʹtsov، نويسنده , , Alexander M. and Trofimov، نويسنده , , Boris A.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
4
From page
3693
To page
3696
Abstract
1-Vinylpyrrole-2-carbaldehydes and 1-vinyl-4,5-dihydrobenzo[g]indole-2-carbaldehyde were synthesized in 56–91% yields from their 1-vinyl derivatives by a modified Vilsmeier–Haack reaction. A low temperature (−78 °C) is required to avoid removal of the N-vinyl group, whereas at elevated temperature (reflux in 1,2-dichloroethane) the latter process leads to direct conversion of 1-vinylpyrroles to pyrrole-2-carbaldehydes.
Keywords
1-Vinylpyrrole , 1-Vinylpyrrole-2-carbaldehydes , Formylation , Vilsmeier–Haack reaction
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1850432
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