• Title of article

    New organic activators for the enantioselective reduction of aromatic imines with trichlorosilane

  • Author/Authors

    Onomura، نويسنده , , Osamu and Kouchi، نويسنده , , Yoshimi and Iwasaki، نويسنده , , Fumiaki and Matsumura، نويسنده , , Yoshihiro، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2006
  • Pages
    4
  • From page
    3751
  • To page
    3754
  • Abstract
    N-Picolinoyl-(2S)-(diphenylhydroxymethyl)pyrrolidine was found to work as an organic activator in the reduction of aromatic imines to the corresponding amines by Cl3SiH. The highest selectivity was 80% ee. These are the first data showing that N-formyl group is not always essential as N-protecting group of pyrrolidine derivatives for the reduction of imines by Cl3SiH.
  • Keywords
    organocatalysis , asymmetric reduction , imines , Optically active amines
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2006
  • Journal title
    Tetrahedron Letters
  • Record number

    1850466

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1850466