Title of article
Regioselective synthesis of N-substituted-4-substituted isothiazolidine-1,1-dioxides
Author/Authors
Cleator، نويسنده , , Ed and Sheen، نويسنده , , Faye J. and Bio، نويسنده , , Matthew M. and Jos Brands، نويسنده , , K.M. and Davies، نويسنده , , Antony J. and Dolling، نويسنده , , Ulf-H.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
4
From page
4245
To page
4248
Abstract
A novel and efficient synthesis of a range of racemic and enantioenriched N-substituted-4-substituted isothiazolidine-1,1-dioxides from epoxides and sulfonamides is described. The critical choice of the activating group for the cyclization event is discussed. The application of this methodology to the synthesis of N-substituted-4,5-disubstituted derivatives is also described.
Keywords
cyclizations , sulfonamides , epoxides , Ring opening reactions
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1850726
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