• Title of article

    Synthesis and functionalization of 2-hydroxypyrimido[4,5-b][1,4]oxazine

  • Author/Authors

    El Kazzouli، نويسنده , , S. and Lavecchia، نويسنده , , G. and Berteina-Raboin، نويسنده , , S. and Guillaumet، نويسنده , , G.، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2006
  • Pages
    4
  • From page
    4437
  • To page
    4440
  • Abstract
    An efficient synthesis of pyrimido[4,5-b][1,4]oxazines is realized using 5-bromouracil. Substitution in the 2-position was performed by palladium-mediated cross-coupling reactions (Suzuki, Stille and carbon–nitrogen bond forming process) and by SNAr reactions. Microwave-heating is also used for high-speed synthesis.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2006
  • Journal title
    Tetrahedron Letters
  • Record number

    1850836