Title of article
Regioselective synthesis of novel 4-aryl-2-ethylthio-7-methyl pyrazolo[1,5-a]-[1,3,5]-triazines
Author/Authors
Insuasty، نويسنده , , Henry and Estrada، نويسنده , , Ricardo Martيn and Cortés-Gutiérrez، نويسنده , , Edward and Quiroga، نويسنده , , Jairo and Insuasty، نويسنده , , Braulio and Abonيa، نويسنده , , Rodrigo and Nogueras، نويسنده , , Manuel and Cobo، نويسنده , , Justo، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
3
From page
5441
To page
5443
Abstract
Pyrazolo[1,5-a]-[1,3,5]-triazines 6a–d were obtained by an efficient one-step reaction from S,S-diethyl aroyliminodithiocarbonates 4a–d and 5-amino-3-methylpyrazole 5 or by an alternative two-step reaction from 5 and aroyl isothiocyanates 8a–d to give initially the thiourea derivatives 9a–d, which after S-ethylation and cyclization afforded compounds 6a–d. The intermediate 7a isolated from reaction between 4a and 5 permitted us to establish the orientation.
Keywords
5-Amino-3-methylpyrazole , S , Aroyl isothiocyanates , S-Diethyl aroyliminodithiocarbonates , 5-a]-1 , 3 , 5]-triazines , Isothioureas , Thioureas
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1851521
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