Title of article
New synthesis of SKF 89976A
Author/Authors
Chang، نويسنده , , Mengyang and Wang، نويسنده , , Si-Yun and Pai، نويسنده , , Chun-Li، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
4
From page
6389
To page
6392
Abstract
Substituted 4,4-diaryl-3-butenyl-1-amines are synthesized in nearly 34–47% overall yields starting from 3-hydroxypiperidine by the regioselective Baeyer–Villiger lactonization, Grignard addition and elimination sequence. This facile strategy was also used to synthesize racemic SKF 89976A.
Keywords
3]oxazepan-7-one , 4 , 3-Hydroxypiperidine , Baeyer–Villiger lactonization , 4-Diaryl-3-butenyl-1-amines
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1852242
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