Title of article
An efficient glycosylation reaction for the synthesis of asialo GM2 analogues
Author/Authors
Sun، نويسنده , , Bin and Pukin، نويسنده , , Aliaksei V. and Visser، نويسنده , , Gerben M. and Zuilhof، نويسنده , , Han، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
4
From page
7371
To page
7374
Abstract
We investigated the coupling reaction of glycosyl donors N-trichloroethoxycarbonyl-galactosamine-O-trichloroacetimidate (2a) and N-p-nitrobenzyloxycarbonyl-galactosamine-O-trichloroacetimidate (2b) with the 4′-OH of lactose derivatives (3a–d) to synthesize key intermediates of asialo GM2 analogues, and found that the glycosylation yield with 2a was 90% or more in all investigated cases.
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1852776
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