Title of article
New C2-symmetric bis(sulfonamide)-cyclohexane-1,2-diamine-RhCp∗ complex and its application in the asymmetric transfer hydrogenation (ATH) of ketones in water
Author/Authors
Cortez، نويسنده , , Norma A. and Rodrيguez-Apodaca، نويسنده , , Ramَn and Aguirre، نويسنده , , Gerardo and Parra-Hake، نويسنده , , Miguel and Cole، نويسنده , , Thomas and Somanathan، نويسنده , , Ratnasamy، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2006
Pages
4
From page
8515
To page
8518
Abstract
C2-symmetric bis(sulfonamide) ligands derived from trans-(1R,2R)-cyclohexane-1,2-diamine were synthesized and complexed with [Cp∗RhCl2]2 in situ and used in the ATH of aromatic ketones with aqueous sodium formate as the hydrogen source. The chiral secondary alcohols were obtained with 90–99% enantioselectivity and in 50–100% yield. Reductions in water were faster than those in isopropanol/KOH.
Keywords
Asymmetric transfer hydrogenation , RhCp? complex , Bis(sulfonamide) ligands , ketones
Journal title
Tetrahedron Letters
Serial Year
2006
Journal title
Tetrahedron Letters
Record number
1853369
Link To Document