Title of article
The effects of IL-6 on CD4 T cell responses
Author/Authors
Dienz، نويسنده , , Oliver and Rincon، نويسنده , , Mercedes، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2009
Pages
7
From page
27
To page
33
Abstract
Cytokines have long been known to profoundly influence the adaptive immune response by determining CD4 T cell differentiation. Although IL-6 has been initially characterized as a B cell growth factor and inducer of antibody production research from our lab and others has revealed over the last years that IL-6 also plays a significant role in CD4 T cell differentiation. This review highlights the variety of ways in which IL-6 affects CD4 effector functions and how this may contribute to different types of diseases.
Keywords
IL-6R , CD4 T cell differentiation , Th1/Th2/Th17 , Autoimmune Disease , IL-21 , T helper response , IL-6 , Allergic airway inflammation
Journal title
Clinical Immunology
Serial Year
2009
Journal title
Clinical Immunology
Record number
1853702
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