Title of article
Stereochemical Prins cyclization: electronic versus steric effects on the synthesis of 2,4,6-trisubstituted tetrahydropyran rings
Author/Authors
Chan، نويسنده , , Kok-Ping and Seow، نويسنده , , Ai-Hua and Loh، نويسنده , , Teck-Peng، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
5
From page
37
To page
41
Abstract
A convenient approach towards the synthesis of both syn- and anti-2,4,6-chlorotetrahydropyrans has been developed. The electronic and steric influences on the stereochemistry of the Prins cyclized products were investigated based on the substituents of the homoallylic alcohol.
Keywords
anti-Tetrahydropyran , Lone-pair inductive effect , Prins cyclization
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1853820
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