Title of article
A mild and efficient chemoselective protection of amines as N-benzyloxycarbonyl derivatives in the presence of La(NO3)3·6H2O under solvent-free conditions
Author/Authors
Chinni Mahesh، نويسنده , , K. and Narasimhulu، نويسنده , , M. and Srikanth Reddy، نويسنده , , T. and Suryakiran، نويسنده , , N. and Venkateswarlu، نويسنده , , Y.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
5
From page
55
To page
59
Abstract
A facile and versatile method for the chemoselective N-benzyloxycarbonylation of amines has been developed by treatment with benzyloxycarbonyl chloride (Cbz–Cl) in the presence of lanthanum(III) nitrate hexahydrate under solvent-free conditions. The method is general for the preparation of N-Cbz derivatives of aliphatic (acyclic and cyclic) and aromatic amines.
Keywords
solvent-free conditions , La(NO3)3·6H2O , N-Benzyloxycarbonylation , Amines
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1853827
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