Title of article
Corrigendum to “Synthesis and post-synthetic derivatization of a cyanine-based amino acid. Application to the preparation of a novel water-soluble NIR dye”: [Tetrahedron Lett. 47 (2006) 8279]
Author/Authors
Chipon، نويسنده , , Bertrand and Clavé، نويسنده , , Guillaume and Bouteiller، نويسنده , , Cédric and Massonneau، نويسنده , , Marc and Renard، نويسنده , , Pierre-Yves and Romieu، نويسنده , , Anthony، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
1
From page
501
To page
501
Abstract
A simple method for the synthesis of carboxyl-free peptides on cellulose membranes was improved and adapted for fully automated SPOT synthesis. Using 1,1′-carbonyl-di-imidazole (CDI) or 1,1′-carbonyl-di-(1,2,4-triazole) (CDT) as an activator within a defined period of time, we were able to reduce the formation of di- or oligomerization of the C-terminal amino acid. The soluble peptides are obtained in a purity range of 60–95% and could be used directly for different biological assays (e.g., CD8 T-cell epitope) that require authentic C-termini.
Keywords
Sulfonation , cyanine dye , Fluorescent amino acid
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1853981
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