• Title of article

    Corrigendum to “Synthesis and post-synthetic derivatization of a cyanine-based amino acid. Application to the preparation of a novel water-soluble NIR dye”: [Tetrahedron Lett. 47 (2006) 8279]

  • Author/Authors

    Chipon، نويسنده , , Bertrand and Clavé، نويسنده , , Guillaume and Bouteiller، نويسنده , , Cédric and Massonneau، نويسنده , , Marc and Renard، نويسنده , , Pierre-Yves and Romieu، نويسنده , , Anthony، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2007
  • Pages
    1
  • From page
    501
  • To page
    501
  • Abstract
    A simple method for the synthesis of carboxyl-free peptides on cellulose membranes was improved and adapted for fully automated SPOT synthesis. Using 1,1′-carbonyl-di-imidazole (CDI) or 1,1′-carbonyl-di-(1,2,4-triazole) (CDT) as an activator within a defined period of time, we were able to reduce the formation of di- or oligomerization of the C-terminal amino acid. The soluble peptides are obtained in a purity range of 60–95% and could be used directly for different biological assays (e.g., CD8 T-cell epitope) that require authentic C-termini.
  • Keywords
    Sulfonation , cyanine dye , Fluorescent amino acid
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2007
  • Journal title
    Tetrahedron Letters
  • Record number

    1853981