Title of article
A new procedure for the synthesis of peptide-derived Amadori products on a solid support
Author/Authors
Stefanowicz، نويسنده , , Piotr and Kapczy?ska، نويسنده , , Katarzyna and Kluczyk، نويسنده , , Alicja and Szewczuk، نويسنده , , Zbigniew، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
3
From page
967
To page
969
Abstract
A new and straightforward solid-phase synthesis of a series of site-specific Amadori-modified peptides is described. The method involves reductive alkylation of the ε-amino groups of lysine with 2,3:4,5-di-O-isopropylidene-β-d-arabino-hexos-2-ulo-2,6-pyranose in the presence of sodium cyanoborohydride on a solid support.
Keywords
Solid-phase peptide synthesis , Amadori rearrangement , glycation
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1854131
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